T-DM1 làm giảm đáng kể nguy cơ tử vong so với trastuzumab (HR không phân tầng = 0,66; 95% CI, 0,51-0,87; P = 0,003). Tỷ lệ sống sót chung sau bảy năm đối với nhóm T-DM1 và trastuzumab lần lượt là 89,1% và 84,4% (chênh lệch 4,7 điểm phần trăm). Tính đến ngày kết thúc thử nghiệm là ngày 5 tháng 10 năm 2023, 70,1% bệnh nhân được chỉ định dùng T-DM1 và 62,0% bệnh nhân được chỉ định dùng trastuzumab vẫn còn sống và tiếp tục tham gia thử nghiệm.

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